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Transfected Stable Cell Lines

Human ERBB2 (S310F) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB2 (S310F) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0196C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ERBB2 (S310F) BAF3 Cell Line is a stable Ba/F3 cell line expressing human ERBB2 with the activating S310F mutation. Lentiviral transduction ensures stable integration, with transgene expression validated by qRT-PCR. Cells are cultured under passage 20.
Target
ERBB2 (HER2) S310F is a hotspot mutation in the extracellular domain that promotes ligand-independent dimerization and downstream signaling. It is implicated in lung, breast, and bladder cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model is ideal for studying ERBB2-driven oncogenesis, therapeutic response to HER2-targeted drugs, and mutation-specific signaling dynamics.

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