Transfected Stable Cell Lines

Human ERBB2 (S310F) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0196C

Product Type

Overexpression Stable Cell Lines

Cell Type

Lymphocytes

Species

Human

Host Cell

BAF3

Source Organ

Lymphatic

Disease

Normal

Storage

Liquid Nitrogen

The human ERBB2 (S310F) BAF3 Cell Line models HER2 point mutation for mechanistic cancer studies and therapeutic screening of HER2-targeted drugs.

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Description

Human ERBB2 (S310F) BAF3 Cell Line is a stable Ba/F3 cell line expressing human ERBB2 with the activating S310F mutation. Lentiviral transduction ensures stable integration, with transgene expression validated by qRT-PCR. Cells are cultured under passage 20.
Target
ERBB2 (HER2) S310F is a hotspot mutation in the extracellular domain that promotes ligand-independent dimerization and downstream signaling. It is implicated in lung, breast, and bladder cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0196C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Lymphocytes

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model is ideal for studying ERBB2-driven oncogenesis, therapeutic response to HER2-targeted drugs, and mutation-specific signaling dynamics.

Inquiring Human ERBB2 (S310F) BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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