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Transfected Stable Cell Lines

Human ERBB2_ERBB3 BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB2_ERBB3 BAF3 Cell Line
Species

Human
Cat.No

ABC-X0200C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ERBB2_ERBB3 BAF3 Cell Line is a murine Ba/F3 model co-expressing human ERBB2 and ERBB3. Lentiviral co-transduction is used for stable gene expression, verified via qRT-PCR. The cell line is expanded under low-passage conditions (<P20). Target ERBB2/ERBB3 heterodimerization potentiates signaling through PI3K/AKT and MAPK pathways, contributing to cancer cell proliferation and survival. Their co-expression models synergistic oncogenic signaling observed in breast and lung cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model is optimized for evaluating dual ERBB2/ERBB3-targeting agents, studying resistance mechanisms, and mapping downstream signaling in heterodimer-driven tumors.

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