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Transfected Stable Cell Lines

Human ERBB4 (D931Y) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB4 (D931Y) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0421C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ERBB4 (D931Y) BAF3 Cell Line is a Ba/F3-derived line stably expressing the D931Y mutant of human ERBB4. This system models IL-3–independent growth mediated by aberrant ERBB4 signaling.
Target
ERBB4 is a receptor tyrosine kinase in the EGFR family. The D931Y point mutation results in ligand-independent activation and promotes oncogenic signaling. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • A platform for elucidating ERBB4 mutation-driven transformation and screening ERBB4 pathway inhibitors.

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