For research use only
| Cat No. | ABC-X0421C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Lymphocytes |
| Species | Human |
| Host Cell | BAF3 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human ERBB4 (D931Y) BAF3 Cell Line, ERBB4, BAF3, Overexpression Stable Cell Lines, Transfected Stable Cell Lines
Human ERBB4 (D931Y) BAF3 Cell Line is a Ba/F3-derived line stably expressing the D931Y mutant of human ERBB4. This system models IL-3–independent growth mediated by aberrant ERBB4 signaling.
Target
ERBB4 is a receptor tyrosine kinase in the EGFR family. The D931Y point mutation results in ligand-independent activation and promotes oncogenic signaling. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0421C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocytes |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | BAF3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
A platform for elucidating ERBB4 mutation-driven transformation and screening ERBB4 pathway inhibitors.