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Primary Cells

Human Esophageal Cancer Peripheral Blood Mononuclear Cells

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Included Diagnoses: Adenocarcinoma (including all subtypes) and Squamous Cell Carcinoma (including all subtypes), Neuroendocrine tumors of the esophagus, Carcinoma of the esophagus.
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Species

Human

Cat.No

ABC-TC4355

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Mononuclear Cell

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peripheral Blood

Disease

Esophageal Cancer

Storage

Liquid Nitrogen

Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Esophageal Cancer Peripheral Blood Mononuclear Cells are mainly derived from the peripheral blood of esophageal cancer patients. They are a mixed cell population, including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are round or oval. These cells play key immune functions in the esophageal cancer microenvironment: T cells mediate tumor-specific killing, NK cells participate in natural immune surveillance, and monocytes can differentiate into tumor-associated macrophages (TAMs) to regulate inflammatory responses by secreting cytokines (such as TNF-α, IL-6).

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Citation

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Application

  • Human Esophageal Cancer Peripheral Blood Mononuclear Cells can be used to evaluate the systemic immune status of patients with esophageal cancer, such as analyzing the abundance of T cell subsets (such as the CD4+/CD8+ ratio), regulatory T cells (Tregs), or myeloid-derived suppressor cells (MDSCs) by flow cytometry, which may predict disease progression or immunotherapy response.

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