+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, Kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human ETV6_cKIT BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0373C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

Human ETV6_cKIT BAF3 Cell Line, ETV6, cKIT, Overexpression Stable Cell Lines, Transfected Stable Cell Lines

Product Image
  • Human ETV6_cKIT BAF3 Cell Line
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ETV6_cKIT BAF3 Cell Line

Description

Human ETV6_cKIT BAF3 Cell Line is a genetically engineered model derived from selected murine pro-B Ba/F3 parental cell line based on customers’ requirement. ETV6_cKIT BAF3 overexpression cell line is generated by stable integration of an exogenous human ETV6-cKIT fusion gene into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The ETV6-cKIT fusion arises from oncogenic rearrangement involving the transcriptional repressor ETV6 and receptor tyrosine kinase c-KIT. This fusion results in ligand-independent activation of downstream signaling, driving leukemogenesis. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0373C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The ETV6_cKIT BAF3 Overexpression Cell Line is a valuable model for investigating fusion-driven acute leukemia and for screening tyrosine kinase inhibitors specific to aberrant c-KIT activation.

  • Online Inquiry
  • Product Reviews

Inquiring Human ETV6_cKIT BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button