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Transfected Stable Cell Lines

Human ETV6_ERBB4 BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ETV6_ERBB4 BAF3 Cell Line
Species

Human
Cat.No

ABC-X0269C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ETV6_ERBB4 BAF3 Cell Line is a fusion-expressing cell model derived from murine BAF3 cells through lentiviral delivery of ETV6-ERBB4. Cells are validated by qRT-PCR and cultured under low passage (<P20). Target The ETV6-ERBB4 fusion results from chromosomal rearrangement and drives oncogenic signaling via aberrant tyrosine kinase activity. It has been observed in hematologic malignancies and promotes cytokine-independent cell growth. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This fusion model allows investigation of ERBB4-mediated leukemogenesis, drug response to tyrosine kinase inhibitors, and resistance mechanisms in preclinical studies.

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