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Transfected Stable Cell Lines

Human ETV6_ERBB4 BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0269C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human ETV6_ERBB4 BAF3 Cell Line enables research on fusion gene oncogenicity and targeted therapy development in hematologic malignancies.

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  • Human ETV6_ERBB4 BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ETV6_ERBB4 BAF3 Cell Line

Description

Human ETV6_ERBB4 BAF3 Cell Line is a fusion-expressing cell model derived from murine BAF3 cells through lentiviral delivery of ETV6-ERBB4. Cells are validated by qRT-PCR and cultured under low passage (<P20). Target The ETV6-ERBB4 fusion results from chromosomal rearrangement and drives oncogenic signaling via aberrant tyrosine kinase activity. It has been observed in hematologic malignancies and promotes cytokine-independent cell growth. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human
Cat.No

ABC-X0269C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This fusion model allows investigation of ERBB4-mediated leukemogenesis, drug response to tyrosine kinase inhibitors, and resistance mechanisms in preclinical studies.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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