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Transfected Stable Cell Lines

Human ETV6_FGFR3 NIH/3T3 Cell Line

  • For research use only

Cat No.

ABC-X0313C
Product Type

Overexpression Stable Cell Lines
Cell Type

Fibroblast
Species

Human
Host Cell

NIH/3T3
Source Organ

Embryo
Disease

Normal
Storage

Liquid Nitrogen

Human ETV6_FGFR3 NIH/3T3 Cell Line facilitates research into ETV6-FGFR3 fusion oncogenes in hematologic malignancies and potential therapeutic strategies.

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  • Human ETV6_FGFR3 NIH/3T3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ETV6_FGFR3 NIH/3T3 Cell Line

Description

Human ETV6_FGFR3 NIH/3T3 Cell Line is a murine fibroblast model expressing the oncogenic ETV6-FGFR3 fusion protein. This cell line is designed for evaluating the role of FGFR3 fusion signaling in tumorigenesis.
Target
The ETV6-FGFR3 fusion results from chromosomal translocation and retains the dimerization domain of ETV6 and the kinase domain of FGFR3, leading to constitutive receptor activation. This fusion has been observed in hematological malignancies such as leukemia.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0313C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Useful for evaluating FGFR-targeted inhibitors, modeling fusion-driven cancers, and conducting drug resistance studies in vitro.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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