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Transfected Stable Cell Lines

Human ETV6_LCK BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ETV6_LCK BAF3 Cell Line
Species

Human
Cat.No

ABC-X0399C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ETV6_LCK BAF3 Cell Line is a genetically engineered model derived from selected murine pro-B Ba/F3 parental cell line based on customers’ requirement. ETV6_LCK BAF3 overexpression cell line is generated by stable integration of an exogenous human ETV6-LCK fusion gene into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
ETV6-LCK is a fusion oncoprotein that aberrantly activates T-cell receptor signaling, contributing to the development of hematologic malignancies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The ETV6_LCK BAF3 Overexpression Cell Line supports investigations into abnormal lymphoid signaling pathways and preclinical evaluation of SRC/LCK-targeted therapeutics.

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