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Transfected Stable Cell Lines

Human FCGR2A_R167 CHOK1 Cell Line

  • For research use only

Cat No.

ABC-X0126C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

CHOK1
Source Organ

Ovary
Disease

Normal
Storage

Liquid Nitrogen

FCGR2A (R167) CHOK1 Cell Line facilitates the analysis of Fc receptor signaling and aids therapeutic antibody development for immune diseases.

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  • Human FCGR2A_R167 CHOK1 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FCGR2A_R167 CHOK1 Cell Line

Description

Human FCGR2A_R167 CHOK1 Cell Line is a stable CHOK1-derived model engineered to express the low-affinity Fc gamma receptor IIA (CD32A) with the R167 variant. Transduction is performed using lentiviral vectors, with transgene expression confirmed via qRT-PCR and passages kept below 20.
Target
FCGR2A (CD32A) mediates IgG immune complex recognition, phagocytosis, and cytokine release. The R167 variant influences receptor affinity and downstream immune activation, with implications in autoimmunity and immunotherapy efficacy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0126C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model is ideal for investigating Fc receptor biology, antibody effector function, and the development of Fc-engineered therapeutic antibodies. It enables high-throughput assessment of IgG subclass interactions and immune modulation.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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