For research use only
| Cat No. | ABC-X0152C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
FCGR3B (NA2) CHOK1 Cell Line serves as a tool for studying neutrophil Fc receptor function and testing monoclonal antibody immune engagement.
Human FCGR3B_NA2 CHOK1 Cell Line is a stable CHOK1 cell model engineered to express the human FCGR3B gene with the NA2 allotype. Transduction is achieved using lentiviral vectors, and expression is validated by qRT-PCR. Cells are expanded under controlled low-passage conditions (<P20). Target FCGR3B (CD16b) is a glycosylphosphatidylinositol-anchored receptor involved in neutrophil activation and immune complex clearance. The NA2 variant is associated with altered immune responses and disease susceptibility. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.
| Species | Human |
| Cat.No | ABC-X0152C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This model supports functional assays on antibody-dependent cellular cytotoxicity (ADCC), IgG interaction, and innate immune regulation, especially in therapeutic antibody development.