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Transfected Stable Cell Lines

Human FGFR2 (E565A) BICC1 BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0189C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human FGFR2 (E565A) BICC1 BAF3 Cell Line enables investigation of FGFR2 mutation-driven oncogenesis and supports targeted therapy development.

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  • Human FGFR2 (E565A) BICC1 BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR2 (E565A) BICC1 BAF3 Cell Line

Description

Human FGFR2 (E565A) BICC1 BAF3 Cell Line is a murine pro-B cell model engineered to express the FGFR2-BICC1 fusion carrying the E565A point mutation. Gene integration is performed using lentiviral vectors, with expression confirmed by qRT-PCR. Cells are maintained under passage 20.
Target
FGFR2 fusions promote constitutive kinase activity and oncogenic signaling. The E565A mutation may alter substrate specificity and downstream pathway engagement in cholangiocarcinoma and other cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0189C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cell model is designed for FGFR2 inhibitor sensitivity studies, signaling analysis, and resistance mechanism elucidation in fusion-driven malignancies.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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