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Transfected Stable Cell Lines

Human FGFR2_BICC1 (V564F) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR2_BICC1 (V564F) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0331C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human FGFR2_BICC1 (V564F) BAF3 Overexpression Cell Line is a stable Ba/F3 model harboring the human FGFR2_BICC1 fusion gene with the V564F mutation, integrated via lentiviral transduction. The edited cells are validated using qRT-PCR and maintained at low passage (<P20). Target The FGFR2_BICC1 fusion results in constitutive FGFR2 signaling, and the V564F mutation further enhances its kinase activity, contributing to oncogenesis in cholangiocarcinoma and other malignancies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line is a powerful model for investigating FGFR2 fusion-driven signaling and drug resistance mechanisms, enabling screening of selective FGFR inhibitors in vitro.

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