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Human FGFR3_BAIAP2L1 BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR3_BAIAP2L1 BAF3 Cell Line
Species

Human
Cat.No

ABC-X0270C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human FGFR3_BAIAP2L1 BAF3 Cell Line is a genetically engineered model based on murine BAF3 cells expressing the FGFR3-BAIAP2L1 fusion construct. Integration is achieved by lentiviral transduction, and expression is validated by qRT-PCR.
Target
The FGFR3-BAIAP2L1 fusion leads to constitutive activation of FGFR3 kinase signaling and has been implicated in multiple cancers including bladder carcinoma. It promotes oncogenesis via PI3K/AKT and MAPK pathways. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model is used for functional analysis of FGFR3 fusions, screening of FGFR inhibitors, and studying oncogenic pathways driven by fusion kinases.

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