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Human FGFR3_TACC3 (R669G) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR3_TACC3 (R669G) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0347C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human FGFR3_TACC3 (R669G) BAF3 Overexpression Cell Line is a genetically engineered model derived from murine BAF3 pro-B cells based on customers’ requirement. This cell line stably expresses the human FGFR3_TACC3 fusion gene containing the R669G mutation, introduced via lentiviral vector transduction. The edited cells are validated by qRT-PCR and maintained at low passage numbers (

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line overexpresses the FGFR3-TACC3 fusion with the R669G point mutation, representing a recurrent event in glioblastoma and other solid tumors. It supports studies on oncogenic fusion proteins, aberrant receptor tyrosine kinase signaling, and resistance to FGFR-targeted therapies. The model is highly useful for evaluating drug responses, understanding transformation potential, and modeling chromosomal rearrangement-driven tumorigenesis in hematopoietic cells.

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