+1 862-686-2696

  • Buy 1 Get 1 FREE for immortalized cells| limited time until end of June

  • Boost Your Research with FREE Freezing Medium

Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, Kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human FLT3 (K663Q) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0022C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocyte
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The FLT3 (K663Q) BAF3 cell line provides a powerful tool for studying leukemia mediated by FLT3 mutations, supporting high-throughput screening.

Product Image
  • Human FLT3 (K663Q) BAF3 Cell Line
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FLT3 (K663Q) BAF3 Cell Line

Description

Human FLT3 (K663Q) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. FLT3 (K663Q) BAF3 mutant cell line is generated by stable integration of exogenous human FLT3 gene harboring the K663Q point mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
FLT3 is a class III receptor tyrosine kinase that plays a crucial role in early hematopoiesis. The K663Q mutation occurs in the juxtamembrane region and is reported to promote constitutive dimerization and kinase activation. Activating mutations in FLT3 are strongly associated with acute myeloid leukemia (AML) and confer poor prognosis. AcceGen offers generation of stable overexpression and mutation-specific cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0022C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The FLT3 (K663Q) BAF3 Cell Line serves as a powerful tool to investigate FLT3 mutation-mediated leukemogenesis and targeted drug sensitivity. This model enables mechanistic studies of IL-3-independent proliferation, JAK/STAT and MAPK pathway activation, and FLT3 inhibitor resistance. It is utilized for high-throughput screening of next-generation FLT3-targeted therapies in AML research.

  • Online Inquiry
  • Product Reviews

Inquiring Human FLT3 (K663Q) BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button