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Transfected Stable Cell Lines

Human FLT3 (N701K) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FLT3 (N701K) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0268C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human FLT3 (N701K) BAF3 Cell Line is a genetically engineered BAF3 model expressing FLT3 with the N701K mutation, established via lentiviral transduction. Cells are expanded at low passage (<P20) and validated by qRT-PCR. Target FLT3 N701K confers resistance to type I FLT3 inhibitors and is emerging as a clinically relevant secondary mutation in AML patients under targeted therapy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Application
  • This cell line supports exploration of mutation-induced resistance and facilitates development of FLT3 inhibitors that retain efficacy against N701K variants.

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