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Transfected Stable Cell Lines

Human GOPC ROS1 BAF3 Cell Line

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  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

Human

Cat.No

ABC-X0027C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocytes

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

The GOPC ROS1 BAF3 Cell Line expresses the human GOPC-ROS1 fusion protein via lentiviral integration. This fusion combines the coiled-coil domain of GOPC with the kinase domain of ROS1, leading to constitutive kinase activation.
Target
GOPC-ROS1 fusion is identified in glioblastoma and other solid tumors. The fusion results in ligand-independent ROS1 activation, triggering downstream MAPK and JAK/STAT pathways. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • This model supports research into ROS1-driven tumorigenesis, drug development for fusion-positive tumors, and resistance mechanism evaluation.

Inquiring Human GOPC ROS1 BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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