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Transfected Stable Cell Lines

Human HRAS (G12A) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human HRAS (G12A) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0319C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human HRAS (G12A) BAF3 Overexpression Cell Line is developed from murine Ba/F3 cells by stably integrating a lentiviral construct expressing HRAS with the G12A point mutation. Expression is confirmed by qRT-PCR and cells are maintained at early passages (<P20). Target HRAS is a proto-oncogene encoding a GTPase involved in mitogenic signaling. The G12A mutation enhances HRAS activity by reducing GTP hydrolysis, contributing to oncogenic transformation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This engineered cell line facilitates the dissection of HRAS-mediated oncogenesis and drug discovery targeting aberrant RAS/MAPK signaling cascades in cancer models.

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