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Transfected Stable Cell Lines

Human HRAS (G13C) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human HRAS (G13C) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0034C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human HRAS (G13C) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. HRAS (G13C) BAF3 mutant cell line is generated by stable integration of exogenous human HRAS gene harboring the G13C mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
HRAS is a member of the RAS superfamily of GTPases that regulate cell signaling cascades, including RAF/MEK/ERK and PI3K/AKT pathways. The G13C mutation disrupts GTP hydrolysis, locking HRAS in a constitutively active conformation. This mutation is implicated in transformation, increased proliferation, and resistance to upstream inhibitors. AcceGen offers generation of stable overexpression and point-mutant cell lines tailored for molecular oncology studies. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The HRAS (G13C) BAF3 Cell Line provides a high-fidelity system for dissecting oncogenic HRAS signaling, assessing mutation-specific drug responses, and modeling disease progression. It is suitable for drug screening, biomarker validation, and mechanistic cancer research.

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