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Transfected Stable Cell Lines

Human HRAS (Q61L) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0324C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

Human HRAS (Q61L) BAF3 Cell Line facilitates studies on constitutive HRAS activation and its effects on oncogenic transformation and targeted therapy.

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  • Human HRAS (Q61L) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human HRAS (Q61L) BAF3 Cell Line

Description

Human HRAS (Q61L) BAF3 Overexpression Cell Line is generated from Ba/F3 cells by lentiviral-mediated stable expression of human HRAS containing the Q61L mutation. The cells are maintained under low passage conditions (<P20) and validated via qRT-PCR. Target The Q61L mutation in HRAS results in defective GTPase activity and persistent activation of the MAPK pathway, contributing to tumor initiation and progression. This alteration is frequently found in bladder, thyroid, and skin cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human
Cat.No

ABC-X0324C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cell model is widely used to investigate HRAS Q61L-induced oncogenesis and to develop therapeutics targeting the RAS signaling axis in HRAS-driven malignancies.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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