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Human Kidney Cancer Peripheral Blood Mononuclear Cells

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Included Diagnoses: Adenocarcinoma (including all subtypes) and Squamous Cell Carcinoma (including all subtypes),&nbsp, Neuroendocrine tumors of the Kidney, Renal Cell Carcinoma, Clear Cell Carcinoma and other carcinomas of the kidney, Urothelial tumors of the kidney.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Kidney Cancer Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4352
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Kidney Cancer
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Kidney Cancer Peripheral Blood Mononuclear Cells are a population of mononuclear cells isolated from the peripheral blood of patients with renal cancer, mainly including lymphocytes (T cells, B cells, NK cells) and monocytes. PBMCs play a core role in immune response: T cells mediate cellular immunity, B cells produce antibodies, NK cells perform natural killing functions, and monocytes can differentiate into macrophages or dendritic cells to participate in antigen presentation. In renal cancer, the composition and function of PBMCs are often abnormal, such as an increase in the proportion of regulatory T cells (Treg) or inhibition of effector T cell function, leading to tumor immune escape.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Kidney Cancer Peripheral Blood Mononuclear Cells can serve as a key model for studying the immune microenvironment of renal cancer and help to analyze tumor-related immunosuppression mechanisms, such as the expansion of regulatory T cells (Tregs), T cell exhaustion, or activation of myeloid-derived suppressor cells (MDSCs). PBMCs can also be used to evaluate the efficacy of immunotherapies, such as PD-1/PD-L1 inhibitors, CAR-T therapy.

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