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Human KIF5B_RET (E732K) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human KIF5B_RET (E732K) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0352C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human KIF5B_RET (E732K) BAF3 Overexpression Cell Line is a genetically engineered model derived from murine BAF3 pro-B cells based on customers’ requirement. The KIF5B-RET fusion gene carrying the E732K mutation is stably introduced into BAF3 cells via lentiviral vector delivery. Clonal validation is performed by qRT-PCR, and cells are kept at low passage numbers (

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line overexpresses the E732K-mutant KIF5B-RET fusion, aiding research on point mutation effects in RET-rearranged tumors. It is useful for studying RET activation, downstream signal transduction, and selective inhibitor resistance. The model supports preclinical evaluation of precision therapies targeting RET mutations and contributes to a deeper understanding of fusion protein biology.

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