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Transfected Stable Cell Lines

Human LMNA NTRK1 BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0002C

Product Type

Overexpression Stable Cell Lines

Cell Type

Lymphocyte

Species

Human

Host Cell

BAF3

Source Organ

Lymphatic

Disease

Normal

Storage

Liquid Nitrogen

AcceGen offers the LMNA-NTRK1 BAF3 cell line, supporting both polyclonal and monoclonal selection, facilitating the exploration of tumor mechanisms.

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Description

Human LMNA-NTRK1 BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. LMNA-NTRK1 BAF3 fusion cell line is generated by stable integration of exogenous human LMNA-NTRK1 fusion gene into Ba/F3 host cells using our optimized transduction of lentiviral vectors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.The LMNA-NTRK1 BAF3 Cell Line serves as a powerful tool to investigate TRK fusion-driven oncogenic mechanisms and therapeutic interventions.

Species

Human

Cat.No

ABC-X0002C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Lymphocyte

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Human LMNA NTRK1 BAF3 Cell Line serves as a valuable in vitro model for studying oncogenic fusion genes and targeted therapies related to NTRK1-driven malignancies. The LMNA-NTRK1 fusion has been implicated in various tumor types, including thyroid carcinoma and soft tissue sarcoma. This cell line enables evaluation of downstream signaling pathways such as MAPK and PI3K-AKT and assessment of selective TRK inhibitors. Researchers can also use it to validate diagnostic biomarkers and explore resistance mechanisms to targeted therapies.

Inquiring Human LMNA NTRK1 BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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