Human Lung Cancer Peripheral Blood Mononuclear Cells

Description

Human Lung Cancer Peripheral Blood Mononuclear Cells are an immune cell population isolated from the peripheral blood of lung cancer patients, comprising lymphocytes (T cells, B cells, NK cells) and monocytes. Round mononuclear cells, suspension growth, weak adhesion.In the lung cancer microenvironment, PBMCs participate in tumor progression or anti-tumor responses through immune regulation. Specifically, T cells can recognize and kill tumor cells, while regulatory T cells (Tregs) may suppress immune responses, promoting tumor immune escape .Likely presence of immune checkpoint molecules (e.g., PD-1, CTLA-4) and Treg markers, but not detailed Monocytes can differentiate into tumor-associated macrophages (TAMs), further influencing the inflammatory state of the tumor microenvironment.Role in tumor immune escape through Tregs and TAMs contributing to immune suppression and tumor progression.