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Primary Cells

Human Lymphatic Endothelial Cells

  • For research use only

Cat No.

ABC-TC3687
Product Type

Immune Cells
Cell Type

Endothelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lymphatic Vessel
Disease

Normal
Storage

Liquid Nitrogen

HLEC from AcceGen Research Laboratories are isolated from human lymph nodes.

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  • Human Lymphatic Endothelial Cells
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Home | Primary Cells | Human Primary Cells | Immune System Primary Cells | Human Lymphatic Endothelial Cells

Description

Human Lymphatic Endothelial Cells (HLECs) are primary cells isolated from human dermal or pulmonary lymphatic vessels and cultured to maintain their physiological function in vitro. These primary endothelial cells form a single-layered lining within lymphatic capillaries and collecting vessels, playing critical roles in fluid homeostasis, immune cell trafficking, and lipid absorption. These cells display a characteristic cobblestone morphology in monolayer culture and express hallmark lymphatic marker CD31 confirmed by immunofluorescence. HLECs respond robustly to lymphangiogenic signals such as VEGF C/VEGFR 3, forming tube-like structures in 3D Matrigel assays. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Lymphatic Endothelial Cells, HLECs, Lymphatic ECs Human, Human Lymph Vessel Endothelial Cells, Lymphatic Vascular Endothelial Cells
Species

Human
Cat.No

ABC-TC3687
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Lymphatic Vessel
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Immune Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HLECs serve as a powerful in vitro platform for studying lymphatic biology and disease mechanisms. They enable researchers to investigate lymphangiogenesis, lymphatic permeability, and immune cell transmigration. They are especially useful in cancer studies exploring how tumors exploit VEGF C/VEGFR 3 pathways for lymphatic metastasis, as well as in anti-lymphangiogenic drug screening assays. Their human origin ensures greater translational relevance compared to animal-derived models, making them ideal for preclinical research.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
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