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Primary Cells

Human Macular Degeneration Peripheral Blood Mononuclear Cells

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Included Diagnoses: Age-related Macular Degeneration, Dry Age-related Macular Degeneration, Wet Age-related Macular Degeneration, Exudative Age-related Macular Degeneration, Acute Macular Degeneration.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Macular Degeneration Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4360
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Macular Degeneration
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Macular Degeneration Peripheral Blood Mononuclear Cells are immune cells derived from the peripheral blood of patients with age-related macular degeneration (AMD), a leading cause of vision loss in older adults. These cells primarily include lymphocytes (T cells, B cells, NK cells) and monocytes. PBMCs play a critical role in immune regulation and inflammatory responses. In AMD, dysfunctional PBMCs contribute to chronic inflammation and oxidative stress, driving retinal pigment epithelium (RPE) and photoreceptor damage.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Macular Degeneration Peripheral Blood Mononuclear Cells can be used to study the immunopathological mechanism of AMD. PBMCs can also be used as a platform for drug screening to test the therapeutic effects of anti-inflammatory drugs (such as glucocorticoids), complement inhibitors (such as Pegcetacoplan) and antioxidants (such as N-acetylcysteine).

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