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Primary Cells

Human Monocyte-Derived Dendritic Cells

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Human Monocyte-Derived Dendritic Cells provide an ideal culture model for the study of the initiation of immune responses, delivery of antigens to dendritic cells, cytokine production, vaccines and Toll-like receptors (TLRs). Dendritic Cells are derived from monocytes that have been cultured with IL-4 and GM-CSF. Our Dendritic Cells are quality tested via flow cytometry to […]
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Home | Primary Cells | Human Primary Cells | Immune System Primary Cells | Human Monocyte-Derived Dendritic Cells
Species

Human
Cat.No

ABC-TC3708
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

DC Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Immune Cells
Key Features

– Backed by AcceGen advanced technology

– Cryopreserved for highest viability and plating efficiency

– Quality-tested for accurate results

– Expert teams to provide timely support and assist best experimental outcomes

Description

Primary Human Monocyte-Derived Dendritic Cells are derived from monocytes in human blood. These cells are cultured in vitro and differentiated by direct induction using a combination of cytokines such as GM-CSF and IL-4. They are monocyte-derived dendritic cells differentiated in vitro from human peripheral blood monocytes.These cells are typically used fresh after 5–7 days of differentiation and do not proliferate in culture.Morphologically, they have a typical dendritic or tree-like appearance and grow by adhering to the wall. As key antigen-presenting cells in the immune system, they can efficiently absorb, process and present antigens. They express surface markers such as CD11c, HLA-DR, CD80, and CD86, indicative of dendritic cell maturation status, detectable by flow cytometry.They have strong migration ability when immature and can effectively activate naive T cells after maturity.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • Human Monocyte-Derived Dendritic Cells can be used in tumor immunotherapy, vaccine development, infectious disease research, and exploration of the mechanisms of autoimmune diseases. In addition, in viral infection research, these cells can simulate the interaction between pathogens and the natural immune system, providing a model for vaccine adjuvant screening and antiviral drug evaluation.

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