Human Neuropathy Peripheral Blood Mononuclear Cells

Description

Human Neuropathy Peripheral Blood Mononuclear Cells are a mixed population of immune cells isolated from the peripheral blood of patients with neuropathy, including subpopulations such as T cells, B cells, NK cells and monocytes. These cells play important roles in immune surveillance, inflammatory responses, and cytokine production, with aberrant activation implicated in peripheral neuropathy pathogenesis. In neuropathic conditions (e.g., diabetic neuropathy, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy), PBMCs contribute to disease progression through dysregulated pro-inflammatory cytokine release (TNF-α, IL-6), autoantibody production, and T-cell-mediated nerve damage.