+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Nucleic Acid Kits
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human NRAS (G12C_Q99L) BAF3 Cell Line

  • BSL

    1

  • 30
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human NRAS (G12C_Q99L) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0282C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human NRAS (G12C_Q99L) BAF3 Cell Line is a genetically engineered model developed from murine pro-B Ba/F3 cells with stable overexpression of human NRAS carrying G12C and Q99L mutations. Lentiviral transduction was used to introduce the dual mutant gene construct into host cells. Cultures are maintained below passage 20. Clonal validation is performed by qRT-PCR.
Target
NRAS G12C_Q99L alters both the GTP-binding domain and effector interactions, leading to aberrant signal transduction. This dual mutation enhances oncogenicity and is of interest in advanced preclinical models of myeloid leukemia and melanoma. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • For research use only

  • This dual-mutant NRAS model is ideal for studying compound mutation effects, inhibitor resistance profiling, and RAS-pathway therapeutic development in hematologic and solid tumors.

  • Online Inquiry
  • Product Reviews

Inquiring Human NRAS (G12C_Q99L) BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button