For research use only
| Cat No. | ABC-X0309C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Fibroblast |
| Species | Human |
| Host Cell | NIH/3T3 |
| Source Organ | Embryo |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human NRAS (G13R) NIH/3T3 Cell Line is engineered to study oncogenic NRAS mutations and their influence on cancer growth and therapeutic resistance.
Human NRAS (G13R) NIH/3T3 Cell Line expresses the G13R mutant NRAS gene in NIH/3T3 cells. This cell model is designed to mimic NRAS-driven transformation in vitro.
Target
The G13R mutation leads to constitutive activation of the NRAS protein, driving uncontrolled cell growth and survival. It is commonly associated with leukemia, melanoma, and colorectal cancer.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0309C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | NIH/3T3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
A valuable system for exploring NRAS-related oncogenesis, drug resistance mechanisms, and therapeutic targeting of Ras pathway mutations.