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Primary Cells

Human Other Cancer Peripheral Blood Mononuclear Cells

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Included Diagnoses: Atypia, Hyperplasia and Precursor lesions, Benign tumors, Fibrous, Fibrohistiocytic and Histiocytic tumors, Germ Cell, Sex Cord and Teratomas, Hamartoma, Medulloblastoma, Hemangioma, Nephroblastoma, Odontogenic tumors, Phyllodes Tumors.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Other Cancer Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4362
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Other Cancer
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Other Cancer Peripheral Blood Mononuclear Cells are isolated from peripheral blood, primarily consisting lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are round or oval. In cancer, the composition and function of PBMCs are often abnormal. For example, the increase of tumor-associated macrophages (TAMs) and regulatory T cells (Tregs) may promote immune escape, while the decreased activity of cytotoxic T cells (CTLs) weakens anti-tumor immunity. In addition, some hematological malignancies (such as leukemia and lymphoma) can directly originate from the malignant transformation of PBMCs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Other Cancer Peripheral Blood Mononuclear Cells can be used to analyze the infiltration of immune cells in the tumor microenvironment, evaluate the immune status of patients, and study the efficacy mechanism of immune checkpoint inhibitors (such as PD-1/PD-L1 inhibitors). They can also be used as markers for liquid biopsy to assist in early diagnosis of cancer and prognosis monitoring.

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