+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Nucleic Acid Kits
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human PDGFRB (W566R) NIH/3T3 Cell Line

  • BSL

    1

  • 7
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human PDGFRB (W566R) NIH/3T3 Cell Line
Species

Human
Cat.No

ABC-X0012C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3

Description

Human PDGFRB (W566R) NIH/3T3 Cell Line is a genetically engineered model derived from selected murine NIH/3T3 parental cell line based on customers’ requirement. PDGFRB (W566R) NIH/3T3 mutant cell line is generated by stable integration of exogenous human PDGFRB gene harboring the W566R point mutation into NIH/3T3 host cells using our optimized transduction of lentiviral vectors.
Target
PDGFRB (platelet-derived growth factor receptor beta) is a receptor tyrosine kinase that regulates mesenchymal cell proliferation and migration. The W566R mutation, located in the juxtamembrane domain, has been shown to induce ligand-independent dimerization and constitutive receptor activation. Aberrant PDGFRB signaling is implicated in myeloproliferative neoplasms, gliomas, and soft tissue sarcomas. AcceGen offers generation of stable mutation-specific or overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • For research use only

  • The PDGFRB (W566R) NIH/3T3 Cell Line serves as a powerful tool to investigate PDGFRB mutation-induced oncogenic transformation and targeted therapy development. This model enables mechanistic studies of receptor autophosphorylation, MAPK/PI3K pathway activation, and anchorage-independent growth. It is utilized for high-throughput drug screening and functional validation of PDGFRB inhibitors in solid and hematologic malignancies.

  • Online Inquiry
  • Product Reviews

Inquiring Human PDGFRB (W566R) NIH/3T3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button