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Transfected Stable Cell Lines

Human PIK3CA_E542K NCI-H1975 Cell Line

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Species

Human

Cat.No

ABC-X0188C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lung

Disease

Carcinoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

NCI-H1975

Description

Human PIK3CA_E542K NCI-H1975 Cell Line is a human lung adenocarcinoma model derived from NCI-H1975 cells, engineered to stably express the oncogenic PIK3CA E542K mutation. Lentiviral vector integration ensures sustained expression, validated by qRT-PCR. Cells are expanded under low-passage culture (

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Application

  • For research use only

  • This model is applicable for PI3K pathway investigation, resistance profiling to PI3K inhibitors, and preclinical testing of targeted therapies in EGFR/PIK3CA-mutant contexts.

Inquiring Human PIK3CA_E542K NCI-H1975 Cell Line

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