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Primary Cells

Human Skin Cancer Peripheral Blood Mononuclear Cells

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Included Diagnoses: Papillary, Follicular, Medullary and other carcinomas (including all subtypes), Adenocarcinoma (including all subtypes), Squamous Cell Carcinoma (including all subtypes), Neuroendocrine tumors of the thyroid (including all subtypes).
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Skin Cancer Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4341
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Skin Cancer
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Skin Cancer Peripheral Blood Mononuclear Cells are a mixed population of immune cells isolated from the peripheral blood patients with skin cancer, including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are typically round or oval in shape. PBMCs are mainly involved in tumor immune surveillance and immune escape regulation in skin cancer. Among them, CD8+ T cells directly kill cancer cells by recognizing tumor antigens, while regulatory T cells (Treg) may inhibit anti-tumor immune responses and facilitate tumor progression. Monocytes may differentiate into tumor-associated macrophages (TAMs), contributing to the modulation of the tumor microenvironment.

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Citation

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Application

  • Human Skin Cancer Peripheral Blood Mononuclear Cells can be used to investigate the tumor antigen-specific killing function of CD8+ T cells, the immunosuppressive mechanism of regulatory T cells (Tregs), and the differentiation process of monocytes into tumor-associated macrophages (TAMs). These cells are also useful for identifying biomarkers related to disease progression or treatment response.

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