Human Skin Cancer Peripheral Blood Mononuclear Cells

Description

Human Skin Cancer Peripheral Blood Mononuclear Cells (PBMCs) are a mixed population of immune cells isolated from the peripheral blood of patients with skin cancer, including lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs are typically round or oval in shape. PBMCs are mainly involved in tumor immune surveillance and immune evasion in skin cancer. Among them, CD8⁺ T cells directly kill cancer cells by recognizing tumor antigens, while regulatory T cells (Tregs) may inhibit anti-tumor immune responses and facilitate tumor progression. Monocytes may differentiate into tumor-associated macrophages (TAMs), contributing to the modulation of the tumor microenvironment. These peripheral blood mononuclear cells provide an accessible model for analyzing systemic antitumor immunity and immune evasion mechanisms in skin cancer.