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Human SLC34A2_ROS1 (F2004C) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human SLC34A2_ROS1 (F2004C) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0089C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human SLC34A2_ROS1 (F2004C) BAF3 Cell Line is a genetically engineered Ba/F3 model stably expressing the SLC34A2-ROS1 fusion with an F2004C activating mutation. The cell line is generated via lentiviral transduction and validated at the transcript level with qRT-PCR. All cell expansions are below 20 passages.
Target
ROS1 fusions like SLC34A2-ROS1 are known oncogenic drivers, and mutations such as F2004C may modulate kinase activity and drug sensitivity. ROS1 mediates proliferative signaling through PI3K, MAPK, and STAT cascades. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model enables detailed investigation of ROS1 fusion-driven tumorigenesis and resistance to ROS1-targeted therapies. It is especially useful in precision oncology drug development and biomarker discovery.

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