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Transfected Stable Cell Lines

Human TNK1 (L600D) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0078C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocyte
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The TNK1 (L600D) BAF3 cell line is an ideal model for studying kinase mutations and signaling pathways, supporting cancer research and drug discovery.

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  • Human TNK1 (L600D) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human TNK1 (L600D) BAF3 Cell Line

Description

Human TNK1 (L600D) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. TNK1 (L600D) BAF3 mutant cell line is generated by stable integration of exogenous human TNK1 gene harboring the L600D point mutation into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
TNK1 encodes a tyrosine kinase involved in cellular stress response and interferon signaling. The L600D mutation is located in the kinase domain and affects its functional activity. Emerging studies suggest TNK1’s dual role in tumor suppression and inflammatory modulation. AcceGen offers generation of stable overexpression or mutation-bearing cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0078C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The TNK1 (L600D) BAF3 Cell Line serves as a powerful tool to investigate kinase domain mutation effects, cell proliferation, and TNK1-dependent signaling cascades. This model enables IL-3 independent growth assays, apoptotic profiling, and kinase inhibitor evaluation. It is used for cancer biology and drug discovery research.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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