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Transfected Stable Cell Lines

Human TNK1 (M596D) BAF3 Cell Line

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Species

Human

Cat.No

ABC-X0404C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocytes

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

Human TNK1 (M596D) BAF3 Cell Line is a murine pro-B cell line engineered to express a mutant form of the human TNK1 gene harboring the M596D mutation. This Ba/F3-based system allows the functional evaluation of mutation-induced transformation in a cytokine-independent manner.
Target
Tyrosine kinase non-receptor 1 (TNK1) plays a regulatory role in signal transduction and cell growth. The M596D mutation is associated with altered kinase activity and oncogenic potential. This model facilitates the study of TNK1-driven transformation and drug sensitivity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • Useful in studying TNK1-mediated signaling mechanisms and screening candidate inhibitors targeting oncogenic TNK1 mutations.

Inquiring Human TNK1 (M596D) BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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