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Human TNK1 (M596D) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human TNK1 (M596D) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0404C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human TNK1 (M596D) BAF3 Cell Line is a murine pro-B cell line engineered to express a mutant form of the human TNK1 gene harboring the M596D mutation. This Ba/F3-based system allows the functional evaluation of mutation-induced transformation in a cytokine-independent manner.
Target
Tyrosine kinase non-receptor 1 (TNK1) plays a regulatory role in signal transduction and cell growth. The M596D mutation is associated with altered kinase activity and oncogenic potential. This model facilitates the study of TNK1-driven transformation and drug sensitivity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Useful in studying TNK1-mediated signaling mechanisms and screening candidate inhibitors targeting oncogenic TNK1 mutations.

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