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Species | Human |
Cat.No | ABC-X0404C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Lymphocytes |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO2 |
Source Organ | Lymphatic |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | BAF3 |
Human TNK1 (M596D) BAF3 Cell Line is a murine pro-B cell line engineered to express a mutant form of the human TNK1 gene harboring the M596D mutation. This Ba/F3-based system allows the functional evaluation of mutation-induced transformation in a cytokine-independent manner.
Target
Tyrosine kinase non-receptor 1 (TNK1) plays a regulatory role in signal transduction and cell growth. The M596D mutation is associated with altered kinase activity and oncogenic potential. This model facilitates the study of TNK1-driven transformation and drug sensitivity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
For research use only