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Transfected Stable Cell Lines

Human TPR_Met (D1228N) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human TPR_Met (D1228N) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0426C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human TPR_Met (D1228N) BAF3 Cell Line is a Ba/F3 line expressing the fusion gene TPR_Met with a D1228N mutation. This mutation enables IL-3–independent proliferation and oncogenic transformation.
Target
The TPR_Met fusion combines the coiled-coil domain of TPR with the MET receptor kinase. D1228N enhances MET kinase activity and contributes to drug resistance. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • A suitable model for studying MET fusion–mediated transformation and screening MET-targeted inhibitors.

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