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Species | Human |
Cat.No | ABI-H0003X |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Immortalized Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Fibroblast-Like |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Synovium |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Immortalized Cell Line |
Immortalized Human Fibroblast-Like Synoviocytes are derived from primary human synoviocytes immortalized by introducing the SV40 large T antigen. Following the primary culture, these cells are cryopreserved. These synoviocytes are involved in the synthesis of synovial fluid, facilitation of joint cavity absorption, regulation of blood/synovial fluid exchange, and inflammation and joint destruction. In vitro, these cells should be avoided repeated freeze-thaw cycles during the culture process.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Immortalized Human Fibroblast-Like Synoviocytes provide an effective in vitro model for studying synovial cell biology and the pathogenesis of joint diseases. They support research into synovial tissue organization and may serve as therapeutic targets. These cells are also employed in high-throughput and high-content screening models, accelerating the discovery and development of treatments for inflammatory and degenerative joint disorders.