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Immortalized Cell Lines

Immortalized Human Lens Epithelial Cell Line – SV40

  • For research use only

Cat No.

ABI-TC170D
Product Type

Immortalized Cell Line
Cell Type

Epithelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Eye
Disease

Normal
Storage

Liquid Nitrogen

The Immortalized Lens Epithelial Cells - SV40 is established from primary cells using Adl2-SV40 adenovirus.

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  • Immortalized Human Lens Epithelial Cell Line – SV40
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Home | Immortalized Cell Lines | Immortalized Human Lens Epithelial Cell Line – SV40

Description

The Immortalised Lens Epithelial Cells – SV40 is established from primary cells (isolated from infant lens epithelial fragments) using Adl2-SV40 adenovirus. The Immortalised Human Lens Epithelial Cells – SV40 provides a homogeneous population of cell for the investigation of the physiology of the normal human lens epithelium and study its response to cataractogenic agents and the human lens specific functions. These cells also provide a unique system for examining the relationship between gene expression and differentiation.

Species

Human
Cat.No

ABI-TC170D
Product Category

Immortalized Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Eye
Disease

Normal
Biosafety Level

2
Storage

Liquid Nitrogen
Product Type

Immortalized Cell Line
Immortalization Method

Serial passaging and transduction with recombinant adenovirus carrying SV40 Large T antigen
Morphology

Polygonal
Quality Control

The Immortalized Human Lens Epithelial Cells react positively with the monoclonal antibody to SV40 large T antigen. Western blot and precipitation are used to confirm the presence of βH- and γ-crystallin, the proteins that are markers for cell differentiation in the lens epithelium. SV40 was observed through IHC (Figure 6).

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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