Immortalized Mouse Microglia

Immortalized mouse microglia, which closely resemble primary microglia, are valuable for investigating key microglial functions These cells can be used to investigate important characteristics such as microglial migration, proliferation, and phagocytosis in response to stimuli. Furthermore, the activation of immortalized mouse microglia in response to exposure to HIV-Tat provides a tool for investigating HIV latency and regulatory mechanisms. By utilizing these immortalized cells, researchers can establish robust cellular models that offer insights into the mechanisms underlying HIV infection, latency, and regulatory processes, thus contributing to advancements in our understanding of neuroinflammatory diseases and potential therapeutic interventions.