| Species |
Human
|
| Cat.No |
AM2278
|
| Product Category |
MicroRNA Agomir/Antagomir |
| Size/Quantity |
2 OD, 4 OD, 50 OD (size by request, 1 OD corresponds to 33 ug)
|
| Shipping Info |
Room Temperature
|
| Storage |
-20°C / -80°C
|
| Product Type |
microRNA Agomir/Antagomir
|
| Label |
FAM, CY3, CY5, etc. (optional)
|
| Component |
hsa-miR-429 Agomir and/or Antagomir (Product Form: Dry Powder)
Agomir N.C and/or Antagomir N.C (optional)
|
| Key Features |
*cover all human, mouse, and rat miRNAs listed in miRBase
*higher stability/inhibitory effects in vivo and in vitro
*more stable, easier to pass the cell membrane and tissue gap
*purified and ready-to transfect cells/be administered by injection, inhalation, feeding
*less reagent use amount with longer effect time
|
Description
Hsa-miR-429 is a specific type of microRNA (miRNA) found in humans. MicroRNAs are small, single-stranded RNA molecules that play crucial roles in regulating gene expression at the post-transcriptional level. Hsa-miR-429 is derived from the precursor miRNA hsa-miR-429, and its mature sequence is typically around 22 nucleotides in length.
MicroRNAs like hsa-miR-429 function by binding to complementary sequences in the 3′ untranslated region (UTR) of target messenger RNA (mRNA) molecules, leading to the inhibition of protein translation or degradation of the mRNA. This regulatory mechanism allows microRNAs to modulate the expression of genes involved in various biological processes, including development, differentiation, proliferation, apoptosis, and metabolism..
Designed to cover the spectrum of human, mouse, and rat miRNAs cataloged in miRBase, these antagomirs offer a superior alternative for inhibiting miRNA function both in vivo and in vitro. Their heightened stability and inhibitory effects distinguish them from conventional miRNA inhibitors. This is attributed to their robust competition with mature miRNAs, impeding their complementary pairing with target genes and, consequently, restraining the regulatory actions of miRNAs.
Why choose MIRacle™ hsa-miR-429 miRNA Agomir/Antagomir from AcceGen?
Enhanced Stability and Inhibitory Effects
These antagomirs exhibit superior stability and sustained inhibitory effects, surpassing traditional miRNA inhibitors.
Improved Cellular Uptake
Their well-designed structure facilitates enhanced cellular uptake, ensuring efficient delivery to target cells.
Versatile Administration
Purified and ready for transfection, these antagomirs can be seamlessly administered through various routes, including injection, inhalation, or feeding.
Long-lasting Effects
With a reduced reagent usage and prolonged effect duration, these antagomirs offer a cost-effective solution for sustained miRNA modulation.
