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Rabbit Corneal Endothelial Cells

  • BSL

    1

  • 53
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Home | Primary Cells | Animal Primary Cells | Rabbit Corneal Endothelial Cells
Species

Rabbit
Cat.No

ABC-TC132W
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial Cell
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Cornea
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Corneal Cell

Description

Rabbit Corneal Endothelial Cells (RCECs) are primary cells derived from rabbit corneal endothelium. In vitro, they establish tight junctions and maintain Na⁺/K⁺-ATPase pump activity, essential for corneal hydration and transparency. They proliferate under explant culture or enzymatic isolation and exhibit polygonal morphology that may transition to fibroblastic under TGF‑β/bFGF stimulation. RCECs can undergo endothelial–mesenchymal transition (EMT) in response to growth factors, leading to α‑SMA and vimentin expression—making them valuable for modeling wound healing and endothelial fibrosis. These cells are widely used in ophthalmic research, tissue-engineering, and therapeutic screening.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only.

  • Rabbit Corneal Endothelial Cells are used to model corneal barrier and pump function in vitro, studying Na⁺/K⁺-ATPase and tight junction formation. They are ideal for wound healing assays and epithelial – mesenchymal transition (EMT) research: TGF‑β and bFGF induce fibroblast-like transition with α‑SMA/vimentin expression. Additionally, they serve as testbeds for tissue-engineered graft development and pharmaceutical evaluation of anti-fibrotic or regenerative agents.

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