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Primary Cells

Rat Neurons-Hippocampal

  • For research use only

Cat No.

ABC-TC4178
Product Type

Rat Primary Cells
Cell Type

Neuron
Species

Rat
Growth Conditions

37 ℃, 5% CO2
Source Organ

Brain
Disease

Normal
Storage

Liquid Nitrogen

Rat Hippocampal Neurons model learning and memory, exhibit polarized processes and synaptic plasticity, linked to Alzheimer’s, release GABA and glutamate.

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  • Rat Neurons-Hippocampal
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Home | Primary Cells | Animal Primary Cells | Rat Primary cells | Rat Neurons-Hippocampal

Description

Rat Hippocampal Neurons are primary neuronal cells isolated from the rat hippocampus—a brain region essential for learning and spatial memory. These cells typically cryopreserved at early passages to preserve native characteristics. These adherent cells are characterized by a complex arborized morphology and strong synaptogenic capacity. In vitro, they form dense, interconnected neural networks and express neuronal markers such as βIII-tubulin (Tuj1), MAP2, and NeuN. Functionally, they regulate synaptic plasticity through mechanisms like long-term potentiation and have been implicated in Alzheimer’s disease pathogenesis, particularly via amyloid-β oligomer-induced upregulation of TLR4. These cells are capable of releasing high levels of neurotransmitter, including GABA and glutamic acid. Their well-established culture protocols and consistent functional properties make them a gold-standard in CNS research.

Species

Rat
Cat.No

ABC-TC4178
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Neuron
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Brain
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Rat Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Rat hippocampal neurons provide a robust in vitro model for neuroscience research. They provide a valuable platform for studying neurophysiology, neural plasticity, and memory storage – areas critical for understanding the mechanisms behind learning navigation, and cognitive function. These neurons are also instrumental in investigating neurological disorders such as Alzheimer’s disease, encephalitis, epilepsy, and amnesia. By investigating hippocampal neurons, researchers gain valuable insights into brain physiology, disease mechanisms, and pathology, supporting the development of novel therapeutic strategies and clinical interventions.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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