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Tumor Cell Lines

RC-K8

  • For research use only

Cat No.

ABL-TC0580

Product Type

Human Lymphoma Cell Lines

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peritoneal Effusion

Disease

Malignant Lymphoma

Product Code

RCK-8; RCK8; Rck8

Advance RC-K8 Cell Line applications in lymphoma research, focusing on t(11;14) chromosomal translocation, lymphoid morphology, and oncogenic pathways.

Product Image

Description

RC-K8 human B-cell lymphoma cells in culture, exhibiting round to polymorphic morphology; scale bar at bottom right.
RC-K8 is a human lymphoma cell line that was originally isolated from the peritoneal effusion of a patient with histiocytic lymphoma. RC-K8exhibits pleomorphic morphology and suspension growth characteristics. Analysis of the RC-K8 chromosome revealed complex abnormalities, including translocations involving chromosomes 11 and 14. RC-K8 cells respond to monoclonal antibodies targeting B cell antigens (B1 and Leu12) and Ia antigens (OKIa1), and they exhibit immunoglobulin gene rearrangements despite the lack of surface and cytoplasmic immunoglobulins.
Product Code

RCK-8; RCK8; Rck8

Species

Human

Cat.No

ABL-TC0580

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Peritoneal Effusion

Disease

Malignant Lymphoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Lymphoma Cell Lines

Application

  • The RC-K8 Cell Line is invaluable for studying lymphomagenesis and pulmonary metastasis in lymphoma. It serves as a model for investigating the antitumor effects of potential drugs, particularly those targeting B-cell lymphoma. Researchers utilize RC-K8 to explore immunotherapy strategies for lymphoma, focusing on key enzymes involved in immune evasion. Additionally, this cell line is pivotal in drug discovery, aiding in the evaluation of novel compounds’ antitumor activity and elucidating their molecular mechanisms against hematopoietic malignancies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring RC-K8

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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