For research use only
| Cat No. | ABC-GF0031 |
| Product Type | Others |
Ciliary neurotrophic factor (CNTF) is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth.
Ciliary neurotrophic factor (CNTF) is a member of the cytokine family, it is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its actions appear to be restricted to the nervous system. CNTF has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracellular CNTF binding subunit (CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks.
| Species | Human |
| Cat.No | ABC-GF0031 |
| Product Category | Cell Culture Media, kits & Reagents |
| Size/Quantity | 20 µg/100 µg/1 mg |
| Shipping Info | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. |
| Storage | -20°C |
| Product Type | Others |
| Concentration | > 90 % as determined by SDS-PAGE |
CNTF is a survival factor for neurons of the peripheral sensory sympathetic and ciliary ganglia. It can promote gene expression, cell survival and differentiation in various types of peripheral and central neurons.