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Recombinant Human IL-21 Protein

  • For research use only

Cat No.

ABC-GF0008
Product Type

Others

The Interleukin-21 (IL-21) is a signaling compound that is a major mediator of the immune response, expressed in activated CD4-positive T-cells.

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  • Recombinant Human IL-21 Protein
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Home | Cell Culture Media, kits & Reagents | Growth Factors & Cytokines | Recombinant Human IL-21 Protein

Description

IL-21 (interleukin 21), also known as IL21, belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).

Species

Human
Cat.No

ABC-GF0008
Product Category

Cell Culture Media, kits & Reagents
Size/Quantity

20 µg/100 µg/1 mg
Shipping Info

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage

-20°C
Product Type

Others
Concentration

≥ 95 % as determined by SDS-PAGE and SEC-HPLC.
Buffer Mix

Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Key Features

< 5 EU per mg of the protein as determined by the LAL method

Quality Control

HPLC-verified. GMP grade is also available

Application

  • IL-21 can be developed for use in cell culture, functional assays, and differentiation studies. IL-21 is a cell growth factor that regulates human NK and cytotoxic T cells, thus is used for NK and T cell culture.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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