For research use only
| Cat No. | ABC-GF0005 |
| Product Type | Others |
Interleukin 5 (IL-5) was originally found as an eosinophil colony-stimulating factor. Subsequent studies have elucidated that it exerts its functions.
IL-5 (interleukin 5), also known as IL5, is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. IL-5 also plays a role in terminal differentiation and survival of eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor.
| Species | Human |
| Cat.No | ABC-GF0005 |
| Product Category | Cell Culture Media, kits & Reagents |
| Size/Quantity | 5 µg/100 µg/1 mg |
| Shipping Info | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. |
| Storage | -20°C |
| Product Type | Others |
| Concentration | > 95 % as determined by SDS-PAGE |
| Buffer Mix | Supplied as powder that is lyophilized from a 0.2 um filtered solution in PBS and Trehalose. |
| Key Features | < 1.0 EU per μg protein as determined by the LAL method |
IL-5 has been shown to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.