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SHC1 Knockout Cell Lysate | ||||
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| Product Name | SHC1 Knockout Cell Lysate | |||
| Price | Get Quote | |||
| Cat.No | ABC-KC1811 | Species | Human | |
| Size/Quantity | 100ug | |||
| Shipping Info | Ice Pack | |||
| Storage | Store SHC1 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. | |||
| Description | This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] | |||
| Stock | Custom | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Host Cell | HEK293T | |||
| Application | For research use only | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Growth Mode | Adherent | |||
| Product Type | CRISPR Knockout Cell Lysate | |||
| Product Image |  | |||
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